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178
Alternativas actuales para la confirmación diagnóstica de tuberculosis en pacientes pediátricos
una prueba negativa (ya sea IGRA o PCT) deben someterse a una
segunda prueba a las 8-10 semanas para detectar a aquellos
sujetos que se encontraban en periodo de ventana cuando se
realizó la prueba inicial (21).
CONCLUSIONES
El bajo rendimiento de los métodos diagnósticos
tradicionales ha llevado a la práctica de tratar la TB pediátrica en
forma empírica con demasiada frecuencia. Si bien es cierto que
en algunos casos, ni aun aplicando los métodos aquí referidos se
podrá confirmar bacteriológicamente la enfermedad, es necesario
en todos los casos de sospecha intentar obtener esta confirmación,
especialmente en regiones con prevalencia elevada de resistencia
a los fármacos antituberculosis. Los programas nacionales
a cargo del control de la tuberculosis tienen la obligación y la
urgencia de fortalecer sus redes de laboratorio para que estos
a su vez puedan ofrecer al clínico estas nuevas opciones para el
diagnóstico oportuno de la tuberculosis.
El autor declara no presentar conflicto de intereses
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