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Neumol Pediatr 2018; 13 (3): 92 - 95
95
Micobacterias no tuberculosas en pacientes con fibrosis quística
MNT que se utilizará para todos los pacientes con FQ (PREDICT)
y un algoritmo prospectivo para el tratamiento de MNT en CF
(PATIENCE) (1).
Es importante considerar el diagnóstico de MNT
en pacientes con FQ y solicitar por lo menos una vez al año
muestras para frotis y cultivo para micobacterias y durante
exacerbaciones que no respondan a tratamiento habitual. Se
debe generar también trabajos que den cuenta de la experiencia
en el diagnóstico y manejo de los pacientes con MNT en los
países de América Latina.
Los autores declaran no presentar conflicto de intereses.
REFERENCIAS
1. Martiniano S, Davidson R, Nick J. Non tuberculous
mycobacteria in cystic fibrosis : Updates and the path
forward. Pediatr Pulmonol 2017 ; 52: S29-S36.
2.
Llerena C, Valbuena Y, Zabaleta A, Gómez T. Enfermedad
pulmonar causada por complejo Mycobacterium avium y M.
abscessus. Acta Med Colomb 2017;42(1):26-29.
3.
Lima CA, Gomes HM, Oeleman MA, Ramos JP, Caldas PC,
Campos CE et al. Nontuberculous mycobacteria in respiratory
samples from patients with pulmonary tuberculosis in
the state of Rondonia, Brazil. Mem Inst Oswaldo Cruz
2013;108(4):457-62.
4. Monteiro JC, Lima KVB, Barretto AB, Furlaneto IP. Clinical
aspects in patients with pulmonary infection caused by
mycobacteria of the Mycobacterium abscessus complex in
the Brazilian Amazon. J Bras Pneumol 2018;44(2):93-98
5. Parkins M, Flot R. Emerging bacterial pathogens and
changing concepts of bacterial pathogenesis in cystic
fibrosis. J Cyst Fibros 2015;14:293-304.
6. Hui SH, Noonan L, Chavada R. Post liposuction
Mycobacterium abscessus surgical site infection in a
returned medical tourist complicated by a paradoxical
reaction during treatment. Infect Dis Rep 2015;7(4):6304.
7. Sousa PP, Cruz RC, Schettini AP,Westphal DC. Mycobacterium
abscessus skin infection after tattoing –cas report. An Bras
Dermatol 2015;90 (5):741-3.
8. Song JY, Jeong HW, Cheong HJ, Kim WJ, Kim MJ. An
outbreak of post-acupunture cutaneous infection due to
Mycobacterium abscessus. BMC Infect Dis 2006;13:6:6.
9. Floto RA, Olivier KN, Saiman L, Daley CL, Herrmann JL,
Nick JA et al. US Cystic Fibrosis Foundation and European
Cystic Fibrosis Society consensus recommendations for the
management of non-tuberculous mycobacteria in individuals
with cystic fibrosis. Thorax 2016;71 Suppl 1:i1-22.
10. Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley
C, Gordin F et al. An oficial ATS/IDSA statement : diagnosis,
treatment, and prevention of nontuberculous mycobacterial
diseases. Am J Respir Crit Care Med 2007;175(4):367-416.
11. Watres V, Ratjen F. Antibiotic treatment for nontuberculous
mycobacteria lung infection in people with cystic fibrosis
(Review). Cochrane Database Rev Dec 2012;CD010004.
doi: 10.1002/14651858.CD010004.pub2.2016 .
12. Jarand J, Levin A, Zhang L, Huitt G, Mitchell JD, Daley CL.
Clinical and Microbiologic Outcomes in Patients Receiving
Treatment for Mycobacterium abscessus Pulmonary
Disease. CID 2011;52(5):565-571.
13. Tissot A, Thomas M, Corris P, Brodlie M. Non Tuberculous
Mycobacteria infection and lung transplantation in cystic
fibrosis: a worldwide survey of clinical practice. BMC Pulm
Med 2018;18:86.